Research at the Center is focused on innovation (i.e. that can have a measurable impact on the society) and at the same time 'blue sky' (i.e. the emphasis is on creativity). Researchers have the freedom to explore and push new boundaries or create new directions. The convergent ecosystem means there are no boundaries between groups or researchers, and teams form to address exciting problems.Institute is having well-equipped laboratories with state of art infrastructure. The Institute has been receiving extramural research funding from DBT, DST, CSIR, Indo-foreign centres in addition to intramural funding and Task Force Projects from ICMR.
“To translate concepts developed in basic biological and clinico-epidemiological research to community for major cancers in the country with an emphasis on their early detection, primary and secondary prevention”.
|Major Equipment Facilities are: -
Real-Time PCR allows the precise quantification of these nucleic acids with greater reproducibility. Advantages of Real-Time PCR include the ease of quantification, greater sensitivity, reproducibility and precision, rapid analysis, better control of quality in the process and a lower risk of contamination.
Provides cell analysis and cell sorting services for cancer research at the highest quality. It enhances the productivity and effectiveness of research by promoting high-content data acquisition, ensuring the highest data quality and consistency, carrying out efficient cell sorting, providing reliable data management, educating and training researchers and consulting in experiment design and evaluation.
|Hybrid capture technology (Hc2)
Hybrid capture is a signal amplification technique, meaning that the chemiluminescent or fluorescent signal is amplified to aid detection, rather than the target DNA being amplified by PCR. Hybrid Capture II remains the current gold standard in HPV diagnostics and is the most widely used HPV assay in clinical laboratories in the United States.
The Histopathology core facility offers a variety of histological techniques. The facility processes, embeds and sections human and animal tissues or cell lines into frozen or paraffin formats and stains these with the standard H&E or special stains, as needed by the researcher to complement their work.
DNA sequencing is the process of determining the nucleotide sequence of a given DNA fragment. Once a nucleic acid sequence has been obtained from an organism, it is stored in silico in digital format. Digital genetic sequences may be stored in sequence databases, be analyzed.
Confocal microscope uses a scanning point of light and a pinhole to prevent out of focus light from reaching the detector. Compared to full sample illumination, confocal microscopy gives slightly higher resolution, and significantly improves optical sectioning.
Fluorescence microscoperefers to a microscope that uses fluorescence to generate an image, whether it is a simpler set up like an epifluorescence microscope, or a more complicated design such as a confocal microscope, which uses optical sectioning to get better resolution of the fluorescent image.